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Canasol, a cannabis-based medication for glaucoma that relieves intraocular pressure symptoms associated with late-stage glaucoma. Also, it did not induce the negative side effects that similar synthetic drugs are known for. Medicines replaced by or used in conjunction with Canasol; TBA ... Alternatives ... Substitutes

Drs. Manley West and Albert Lockhart, developed two drugs, canasol and cantimol, that effectively treated glaucoma. Cantimol is a combination of canasol, an alpha agonist and timolol maleate, a beta blocker. * Read more History on Canasol

Smoking ganja has long been known to cause vasodilation and ocular hypotension, however the identification of CB1 receptors on the eye allow for topical application of THC and CBD. In addition recent studies have shown that glaucoma patients generally have low anandamide levels. Anandamide is one of the body's natural cannabinoids.  Read >> MORE >>

How Medical Cannabis Reduces Eye Pressure and Controls Eye Diseases | Cannabis has been proven time, and time again, to be a useful and effective anti-inflammatory for a range of different conditions. Many studies find that Cannabis reduces Glaucoma-related inflammation. "Canasol eyedrops, (a liquid Cannabis based formulation) has been demonstrated to be effective in lowering intraocular pressure, and has also been shown to potentiate the effectiveness of other widely-used glaucoma drugs such as Timolol." -- Dr. Manley West, Pharmacologist, University of the West Indies, Jamaica, Mon  Click >> HERE >> for more.

Glaucoma Treatment: Eye Drops and Other Medications | Most treatments for glaucoma are designed to lower and/or control intraocular pressure (IOP), which can damage the optic nerve that transmits visual information to the brain. Glaucoma eye drops often are the first choice over glaucoma surgery and can be very effective at controlling IOP to prevent eye damage. If you are a good candidate for glaucoma eye drops, you may be prescribed more than one type to achieve the best IOP control. In fact, many types of these drops can enhance the effects of other types. Depending on your general health and other medical conditions, however, you may be a poor candidate for glaucoma eye drops. This is because medications placed in the eye are absorbed into the conjunctival blood vessels on the eye's surface. A certain percentage of the active ingredient of the medication, though small, will enter the bloodstream and may adversely affect functions such as heart rate and breathing.

Likewise, some types of eye drops may worsen certain existing medical conditions such as asthma. Some glaucoma drugs also can interact with other common medications such as digitalis, prescribed for heart conditions. So make sure you discuss these issues with both your family physician and your eye doctor. Types of Glaucoma Eye Drops | Glaucoma eye drops are classified by the active ingredient chemical that helps make the drug work. Also, many of the glaucoma eye drops listed here are available in generic forms at your pharmacy. Prostaglandins. Drugs known as prostaglandins used in eye drops often have the best user compliance because they are required only once daily. Prostaglandins generally work by relaxing muscles in the eye's interior structure to allow better outflow of fluids, thus reducing buildup of eye pressure.

These drugs have a few common side effects, including stinging and burning when put in the eye, eye color change (darkening of the eye) due to an increase of pigmentation in the iris, and lengthening and curling of the eyelashes. (In fact, the eyelash growth side effect eventually led to the development of an eyelash-lengthening drug called Latisse, which is available by prescription.) FDA-approved prostaglandins include Xalatan (Pfizer), Lumigan (Allergan), Travatan Z (Alcon) and Rescula (Novartis). Many glaucoma specialists now report that prostaglandins have taken the lead in recent years as a first-line therapy for glaucoma (EyeWorld, January 2007). Various glaucoma eye drops are classified by the active ingredient chemical that helps make the drug work. Beta-blockers. Used in a variety of glaucoma eye drops, beta-blockers were at one time the drugs of first choice in treating glaucoma. These drugs work by decreasing fluid (aqueous) production in the eye and now are often prescribed as an adjunct to or in combination with prostaglandins.

Alpha-adrenergic agonists. These drugs work by decreasing rate of aqueous humor production and can be used alone or in combination with other anti-glaucoma eye drops. Common side effects associated with this classification of eye drop include red or bloodshot eyes (ocular injection), upper lid elevation, an enlarged (dilated) pupil and itching. The FDA-approved drugs in this class include Iopidine (Alcon), Alphagan (Allergan). and Alphagan-P (Allergan). Carbonic anhydrase inhibitors. These drugs work by decreasing rate of aqueous humor production. They are usually used in combination with other anti-glaucoma eye drops and not alone. This classification of drug is also used in oral form (pills).

Common side effects experienced with this classification of eye drop include burning, a bitter taste, eyelid reactions and eye redness (ocular injection). The FDA-approved eye drops in this class include Trusopt (Merck) and Azopt (Alcon). The systemic (pill) form of carbonic anhydrase inhibitors (CAI) are Diamox (Sigma), Neptazane (Wyeth-Ayerst) and Daranide (Merck, Sharp, & Dohme). About half of patients cannot tolerate oral CAIs due to their systemic side effects, which include fatigue, depression, loss of appetite, weight loss, loss of libido, kidney stones, metallic taste and tingling in fingers and toes (peripheral neuropathies). *  SOURCE >> Click HERE >> *  Click >> - here - for more on medical cannabis and Glaucoma.

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Resources

Where to get, how to make: Medi-Grace Pharmaceuticals has been sold and does not produce Canasol anymore. We do not know of any other producer. Dr. West, RIP, has passed on - (Mar 17,1929 - Apr 24, 2012). MERCY does not have any Canasol nor do we know of a resource. There is a recipe for an eye-wash on our Bulletin Board.

CONTACTS

Medi-Grace Pharmaceuticals | Medi-Grace Pharmaceuticals has been sold and does not produce Canasol anymore. Read more about the sale in the >> News section. We will post any information about any other Businesses in the >> Biz section of this page.

Canasol and Asmasol | After ten years of continuous and diligent research, pharmacologist, Professor Manley West and ophthalmologist, Dr. Albert Lockhart developed an eye drop, Canasol, specifically to treat the eye disease, glaucoma. Glaucoma is estimated to affect 3% of the Jamaican population and causes pain, visual disturbances and even blindness.  Click >> - HERE >> for more and to make contact.

Dr Albert Lockhart | Ophthalmologist, co-developer of Canasol * 7 Melmac Ave Kingston 5 Jamaica * 876-926-2750 -or- 876-926-8914  Click >> HERE >>

Medicanja Limited | was established in December 2013 by Dr. Henry Lowe to chart the way forward in the development of a medical marijuana industry in Jamaica. Cannabis, known locally as ganja, has long been regarded as a plant with outstanding medicinal properties.  Learn more, click >> - HERE >>

People, Organizations, Businesses and other resources   will be listed here as we learn about them. Know of one? Post a Note, Send a Message, and Spread the Word!  

News

GraceKennedy Announces the Sale of MediGrace | GraceKennedy Limited announces the sale of Medi-Grace Limited to Smith Russell & Company Limited, a company which is engaged in the distribution of pharmaceutical and consumer products. It is expected that the sale will be completed by August 31, 2006. Medi-Grace Ltd. is involved in the distribution of pharmaceutical and consumer products, and represents such well known companies as Eli Lilly, Merck Sharp & Dohme, and Pfizer Consumer Health. It is expected that under the new ownership, Medi-Grace will continue to operate as an independent company focusing on the pharmaceutical industry. GraceKennedy Ltd. also operates a similar business which is involved in the distribution of consumer items called World Brands Ltd. Based on the terms of the agreement, certain consumer products with the brand names, Dial, Soft Sheen and Energizer now carried by Medi-Grace will be transferred to World Brands Ltd.  Click >> HERE >> for more.

Cannabis For Glaucoma Is The Real Deal; No Longer A Joke To Get A Medical Card, Marijuana Helps Glaucoma | (Nov 10, 2016) Glaucoma patients are among the country's most prolific medical cannabis users. Cannabis has been shown to effectively reduce intra-ocular pressure (IOP) and in some cases can even halt the progression of glaucoma. Many studies since the 1970's have proven that cannabis is definitely effective in reducing IOP. One of the most recent studies conducted in 2014 shows that the cannabinoids in the plant are effective in reducing IOP in glaucoma patients. The study also found that cannabis possesses neuroprotective characteristics that can help patients prevent glaucoma. One of the most notable studies exploring cannabis for glaucoma dates back to the 60's. Professor Manley West, a pharmacologist, worked with ophthalmologist Dr. Albert Lockhart to research about the potential benefits of cannabis for the condition. They began to analyze cannabis use among Jamaican communities and even developed eye drops containing cannabis called Canasol, which was sold in Jamaica. Canasol was effective in reducing IOP, giving it as much potential as a treatment for glaucoma as conventional medications. Canasol is still used around the world and doesn't contain any of the psychoactive compounds of cannabis.  Click >> HERE >> for more.

Unravelling the Science behind Ganja | (June 6, 2016) The University of the West Indies has revived the ganja research programme it began in the 1970s as it prepares to launch Jamaica as a global "powerhouse" for cannabis research; as famous for its products and services as it already is for reggae and the good 'ol sensi weed'. Aside from ongoing research into the properties and effects of Cannabis, the UWI was among the first in the world to successfully develop medicines from the plant. Its work, going back to 1972 when ophthalmologist Albert Lockhart and pharmacologist Dr. Manley West began investigating the anecdotes of fishermen who attributed their exceptional night-vision to their consumption of 'ganja teas'.

From their research, the Department of Pharmacology in 1987 released the Canasol (TM), eye drops to treat glaucoma and followed that success in later years by a number of pioneering marijuana-derived pharmaceuticals: Asmasol for asthma; Cantivert also used to treat glaucoma; Canavert for motion sickness and Cansens for treating viral infections. "We are expecting that many products will be produced and have to be tested and quality checked for them to be marketed. We also expect the USDA will soon come up with regulations on cannabis-derived medicines and we are preparing to meet them," Lindsay said. Construction of the UWI Mona Cannabis Research Centre and supporting facilities to expand the institutions research capacity and house its partners is estimated to cost some US 4million dollars. McDonald is expecting that funding from partners will equip and build the facility as "their contribution to UWI's 40-year cannabis research legacy, accommodation and the prestige of brand-Jamaica".  Click >> HERE >> for more.

Jamaican ganja - the race against time; Three-day conference at UWI will tell law-makers opportunities slipping away | (May 22, 2014) JAMAICA is already over 40 years behind in decriminalisation of ganja and a three-day conference which kicks off today at the University of the West Indies (UWI) will signal to legislators here that time is not on Jamaica's side. "We are 40 years late," said Dr Albert Lockhart, a leading opthalmologist who helped pioneer marijuana derived medicines such as Canasol for treating glaucoma, the eye disease and Asmasol for asthma sufferers.

Lockhart, and the late Dr Manley West of the UWI intensified medical research on ganja in 1972 after then Health Minister Dr Kenneth McNeill invited them to address parliamentarians on their work and gave them permission to collect, transport and do research on the weed within the bounds of Jamaica. He said Canasol changed the thinking of many persons about glaucoma when it hit the market. The drug gained favour with glaucoma sufferers because, unlike other drugs, it protected the optic nerve, while lowering eye pressure. "Our research found that when ganja was smoked it increased blood flow into the eye. That put us on to Canasol. We had to produce an eye drop because we don't promote smoking," Lockhart disclosed. "Anything smoked opens the smoker to cancer of the lips, throat and lungs," he noted. "Smoking of tobacco can cause heart problems."  Click >> HERE >> for more.

Did you know that it was a Jamaican who: Created Canasol, a ganja-based eye-drop for glaucoma treatment | (Feb., 2014) Canasol was developed through the hard work and scientific research of two notable Jamaicans: pharmacologist, Professor Manley West, and ophthalmologist, Dr Albert Lockhart. It was an important breakthrough drug as it was the first glaucoma eye medication in the Caribbean to be developed at UWI, Mona, and it does not induce the negative side effects that similar synthetic drugs are known for. Professor West remembers being told by country folk that washing their eyes in ganja water made them see better, and fishermen claimed that drinking ganja tea improved their vision, particularly at night. Meanwhile, Dr. Lockhart noted that his Rastafarian patients who used ganja, had few incidences of glaucoma. From these observations, the two men became interested in working with ganja in order to discover its potential medical benefits. Ten years later, Canasol was the result.  Click >> HERE >> for more.

Cannabis Unmasked; What It Is and Why It Does What It Does | (June, 2010) The Cannabis sativa plant has had a long, colourful and often controversial association with mankind. Originally cultivated to make hemp, a soft and durable fibre that was used extensively in the pre-industrial era for the production of rope, textiles and paper, it is also one of the oldest herbal remedies known to man, with texts from ancient China and India detailing its use as a treatment for a variety of illnesses. Even Queen Victoria of Britain is reported to have used it as a preparation for the treatment of menstrual cramps. Despite this wide variety of uses and its extensive commercial production (up to today over 40,000 hectares of hemp are under cultivation worldwide) cannabis is best known for its psychoactive properties and its association with recreational drug use (marijuana). A new era of understanding began in 1964 when the primary active ingredient of cannabis, delta-9-tetrahydrocannabinol (THC) was identified. Advances in cannabinoid physiology proceeded slowly over the next two decades but of note during this period was the contribution made by two Caribbean scientists, Manley West and Albert Lockhart. Based at UWI's Mona Campus, West and Lockhart started their journey in cannabinoid research when they noted (i) a reduction in glaucoma among Rastafarians who traditionally used cannabis and (ii) persons from rural communities who used eyewash purportedly derived from cannabis claimed improved eyesight. This triggered ten years of pioneering research that culminated with the development and patent of a drug, Canasol, for the treatment for glaucoma. *  Click >> HERE >> - for more.

News; Articles, Stories, Sources and other resources   will be listed here as we learn about them. Know of one? Post a Note, Send a Message, and/or Spread the Word!  

History

According to various websites: CANASOL an ophthalmic drop solution prepared from cannabis sativa which contains 0.3% active solid. Canasol's research has proven this product effective to reduce the adverse symptoms of glaucoma by reducing intraocular pressure and having no side effects. This product has been approved by the Ministry of Health of Jamaica. Small wonder then that most new modern-day Cannabis based pharmaceuticals are making their appearance OUTSIDE of the US, in places like Jamaica. *  Click >> HERE >> - for more.

Albert Lockhart and Manley West began studying in 1964 the health effects of traditional cannabis use in Jamaican communities. They developed, and in 1987 gained permission to market, the pharmaceutical "Canasol", and began distribution in 1987. As late as 2003, it was still being distributed in the United Kingdom, several US states, and several Caribbean nations. It was notable for being one of the first cannabis-containing pharmaceuticals to be developed for the modern pharmaceutical market and being one of the few such pharmaceuticals to have ever been legally marketed in the United States.

The product, a derivative from cannabis (ganja, "marijuana"), was at first received with much scepticism and doubt, but according to ophthalmologist Dr. Albert Lockhart, one of the developers of the product, patients from Florida, California, Pennsylvania, Washington D.C., New York and Massachusetts in the United States were using it. "We have to try to educate people and let them know that Canasol does not contain any psychoactive agents" from ganja, he said.

The product was distributed in Jamaica by Medi-Grace Limited and, according to Dr. Lockhart, they also exported to England, some Caribbean islands, and it was sold directly based on doctor's prescriptions from the United States. According to sources at Medi-Grace Limited, an average of 400 units were sold per month, and pharmacists across Jamaica agreed that "the product sells like hot bread." "There is a great demand for the product," Mrs. C. Law a pharmacist at Dolphin's Pharmacy in Kingston said, adding that persons even send from abroad to get it.  Click >> HERE >> for more.

JAMAICA, THE LAND OF GENTLE BREEZES AND MEDICAL CANNABIS: | When one thinks of Jamaica, one usually thinks of travel, tourism, and white sandy beaches. However, it is now also gaining more and more attention as the land where (while still illegal) Cannabis medicines are beginning to flourish. CANASOL an ophthalmic drop solution prepared from cannabis sativa which contains 0.3% active solid. Canasol's research has proven this product effective to reduce the adverse symptoms of glaucoma by reducing intraocular pressure and having no side effects. This product has been approved by the Ministry of Health of Jamaica.  Click >> HERE >> for more on this. *  Click >> here << for more on medical cannabis in Jamaica.

Professor the Hon. Manley West, OM | (Mar 17,1929 - Apr 24, 2012) Pharmacologist who conducted pioneering research of the marijuana plant, leading to the development of specialty medicines for glaucoma and other disorders. Glaucoma is a leading cause of preventable blindness and is estimated to affect three per cent of the Jamaican population. Today, many persons worldwide affected by disease are receiving relief through the use of the drugs developed from this research done at the Mona Campus.  SOURCE >> - HERE >>

Renowned Jamaican scientist Dr. Manley West | Dr West was a scientist who taught pharmacology at the University of the West Indies, Mona. Significantly, with Dr Albert Lockhart, he developed Canasol, a drug for the treatment of the eye disease, glaucoma, from cannabis, or ganja. Born in Portland, West attended the Titchfield High School. He graduated from the University of London, England, in 1967 with a Doctor of Philosophy in pharmacology. His career at the UWI began as assistant lecturer in pharmacology in 1964, from which position he was promoted to lecturer and internal examiner in pharmacology in 1968. Thereafter, in 1975, West served as acting head of the Department of Pharmacology and in that same year was appointed head of the Department of Pharmacology and chief internal examiner. He was appointed professor of pharmacology in 1981. *  Click >> HERE >> - for more.

more History about Canasol and related;   will be listed here as we learn about it. Got info? Post a Note, Send a Message, and/or Spread the Word!  

Bulletin Board, most recent

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Friday, May 29 at 11:56 PM:
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Thursday, August 22 at 08:30 AM:
Jorge Flores from Piedras Negras Coahuila Mx wrote:
" Where can I buy Canasol? Also which is best for Glaucoma, Canasol or Cantimol? "

Monday, September 3 at 11:56 AM:
Canasol is The Best Treatment for Glaucoma "The Eye Disease" from USA wrote:
"*My mother have been suffering from Glaucoma for a very long time now. Last year i started doing some research on her condition and i found out that Canasol is the best treatment of the eye disease, Glaucoma. A friend recommended me to E-mail: (info.cannabismedsdelivery@gmail.com) where i bought 5 bottles and it was ship to me. I very happy today because my mother is fine and Glaucoma FREE!! "Life is too short so Google it" "

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Monday, May 14 at 03:20 PM:
Rene Rosas from México wrote:
" Do you know who sale in Mexico this product? "

Sunday, January 14, 2018 at 07:26 PM:
Maria Moussalli from argentina wrote:
" soy oftalmologa eapecialista en glaucoma quisiera saber como puedo comprar para mis pacientes gracias "

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